The Bible indicates that there will be a great apostasy during the end times. The “great apostasy” is mentioned in 2 Thessalonians 2:3. The KJV calls it the “falling away,” while the NIV and ESV call it “the rebellion.” And that’s what an apostasy is: a rebellion, an abandonment of the truth. The end times will include a wholesale rejection of God’s revelation, a further “falling away” of an already fallen world.
In 2 Thessalonians 2:3, Paul makes it clear that the day of the Lord, a time of worldwide judgment (Isaiah 13:6; Obadiah 1:15), will not transpire until two things happen. First, the falling away, or great apostasy, must occur. Second, the “man of lawlessness” must be revealed, he who is called the “son of perdition,” also known as the Antichrist. Once this person makes himself known, the end times will indeed have come. Numerous speculations about the identity of the man of sin, beginning in the first century, have included Caligula, Caius Caesar, Mohammed, Napoleon, and any number of Roman popes. None of them were the Antichrist.
The man of lawlessness, according to 2 Thessalonians 2:4, is the one “will oppose and will exalt himself over everything that is called God or is worshiped, so that he sets himself up in God’s temple, proclaiming himself to be God.” Clearly, this has not yet happened; no one since Paul’s time has set himself up as God in the Jewish temple. Two thousand years have passed since the epistle was written, and the “day of the Lord” has not yet come. Paul assures us that it will not come until the falling away comes first.
The Greek word translated “rebellion” or “falling away” in verse 3 is apostasia, from which we get the English word apostasy. It refers to a general defection from the true God, the Bible, and the Christian faith. Every age has its defectors, but the falling away at the end times will be complete and worldwide. The whole planet will be in rebellion against God and His Christ except for The Church. Every coup requires a leader, and into this global apostasy will step the Antichrist.
Jesus warned the disciples concerning the final days in Matthew 24:10–12: “At that time many will turn away from the faith and will betray and hate each other, and many false prophets will appear and deceive many people. Because of the increase of wickedness, the love of most will grow cold.” These are the characteristics of the great apostasy of the end times